狠狠色综合7777久夜色撩人_亚洲AV激情高潮抽搐乱色_人妻丰满熟妇av无码区HD_哺乳挤奶一区二区三区免费看

關鍵詞搜索: 3D細胞培養相關產品,多肽毒素,原代細胞,細胞因子,抗體,試劑盒,各類細菌、病毒熒光定量PCR試劑盒,轉基因檢測儀器和耗材等。

你的位置:首頁 > 產品展示 > > 離子通道研究用多肽毒素 >smartox 多肽(tai)毒素

產(chan)品詳(xiang)細頁

smartox 多肽毒素

簡要(yao)描述:Smartox Biotechnology是(shi)*一(yi)家專門生(sheng)產動物毒液多肽(tai)毒素,用于細(xi)胞(bao)離子(zi)通道功能研究的生(sheng)物醫藥公司。多肽(tai)毒素在生(sheng)物制藥領(ling)域具(ju)有重要的使(shi)用價(jia)值(zhi)。

  • 產品型號:
  • 廠商性(xing)質:代理商
  • 更新(xin)時間:2023-10-22
  • 訪  問(wen)  量:4704

產品介紹

Smartox-biotech ---離子通道研究用多肽毒素的專(zhuan)業(ye)化生產商

 

Smartox Biotechnolgy的多肽毒素產品如下:

 

1. 作用于鈉離子通道(Sodium channel)的毒(du)素

Toxin name

Catalog #

Target

Phrixotoxin-3

13PHX003

Selective blocker of Nav1.2

µ-conotoxin GIIIB

CON020

Selective blocker of Nav1.4

µ-conotoxin CnIIIC

CON021

Selective blocker of Nav1.4

μ-conotoxin PIIIA

08CON006

Selective blocker of Nav1.4

Jingzhaotoxin-III

12JZH003

Selective blocker of Nav1.5

ProTx-II

07PTX002

Selective blocker of Nav1.7

ProTx-II Biotin

12PTB002

Selective blocker of Nav1.7

ProTx-I

12PTX001

Blocker of Nav1.8, Nav1.2, Nav1.5, Nav1.7

Huwentoxin-I

07HWT001

Blocker of TTX-S

Huwentoxin-IV

08HWT002

Blocker of TTX-S

Hainantoxin-III

13HTX003

Blocker of TTX-S

Hainantoxin-IV

12HTX001

Blocker of TTX-S

GsAF-I

12GSF001

Blocker of TTX-S

GsAF-II

12GSF002

Blocker of TTX-S

 

2. 作用于鉀離子通道(Potassium channel)的毒素

Toxin name

Catalog #

Target

KCa channels

Apamin 蜜蜂神經毒素

08APA001

SK1, SK2, SK3

Charybdotoxin 蝎毒素(su)

11CHA001

KCa1.1, KCa3.1 - Kv1.2, Kv1.3, Kv1.6

Iberiotoxin

12IBX001

KCa1.1

Leiurotoxin 1 (Scyllatoxin)

10LEI001

SK1, SK2, SK3

Tamapin

10TAM001

SK1, SK2, SK3

Kaliotoxin-1

08KTX002

BK, Kv1.1, Kv1.2, Kv1.3

Kv channels

ShK

08SHK001

Kv1.3, Kv1.1, Kv1.4, Kv1.6

TMR-ShK

SAT001

Kv1.3, Kv1.1

Margatoxin

08MAG001

Kv1.3

(Dap22)-ShK

13SHD001

Kv1.3

AD-1

13ADW001

Kv1.3

HsTx1

08NEU001

Kv1.3, Kv1.2

Agitoxin-2

13AGI002

Kv1.3, Kv1.1

Maurotoxin

08MAR001

Kv1.2, KCa3.1

Guangxitoxin 1E

11GUA002

Kv2.1, Kv2.2

Stromatoxin 1 NEW

SCT01

Kv2.1, Kv2.2

Kaliotoxin-1

08KTX002

BK, Kv1.1, Kv1.2, Kv1.3

Charybdotoxin

11CHA001

KCa1.1, KCa3.1 - Kv1.2, Kv1.3, Kv1.6

Phrixotoxin-2

PHX002

Kv4.2, Kv4.3

AmmTx3 NEW

AMX001

A-type potassium channels

Inwardly rectifying potassium channels

TertiapinQ

08TER001

Kir1.1, Kir3.1/3.4, Kir3.1/3.2-KCa1.1

hERG/Kv11.1

BeKm-1

13BEK001

ERG1

 

3. 作用于鈣離子通道(Calcium channel)的毒素

Toxin name

Catalog #

Target

High voltage-gated Ca2+ channels

ω-agatoxin IVA

11AGA001

P/Qtype

ω-Conotoxin MVIIC

08CON002

P/Qtype, N-type

ω-Conotoxin MVIIA

08CON001

N-type

ω-Conotoxin GVIA

08CON003

N-type

ω-Conotoxin SO3

08CON013

N-type

Huwentoxin I

07HWT001

N-type

ProTx-II

07PTX002

T-type, L-type

Intermediate voltage-gated Ca2+ channels

SNX482

08SNX002

R-type

Low voltage-gated Ca2+ channels

ProTx-I

12PTX001

T-type

ProTx-II

07PTX002

T-type, L-type

Ryanodine receptors

Maurocalcine

07PAU001

Ryr1

 

4. 作用于氯離子通道(Chloride channel)的毒素

Toxin name

Catalog #

Target

Chlorotoxin

08CHL001

Blocker of small conductance Cl- channels

GaTx1

13GTX001

Selective blocker of CFTR channel

GaTx2

10GTX002

Selective blocker of ClC-2 channel

 

5. 作用于乙酰膽堿受體(Acetylcholine receptor)的毒素

Toxin name

Catalog #

Target

α-conotoxin PeIA

13CON017

α9α10, α3β2 subunits

α-Conotoxin PrXA

13CON016

α1/β1/ε/δ, α1/β1/γ/δ subunits

Waglerin-1

12WAG001

MusclenAChR

α-conotoxin MI

08CON012

α1/δsubunits

α-conotoxin GI

08CON005

α/δsite

α-conotoxin IMI

08CON011

α7 homomeric nAChR

α-conotoxin GID

CON019

Blocker of α3β2, α7 and α4β2 nAChRs

 

6. 含N-甲基-D-天冬氨酸NR2B

(NMDA, NR2B containing N-methyl-D-aspartate)

Conantokin-G

選擇性、特(te)異性抑(yi)制(zhi)含NR2B的NMDAR。Conantokin-G能劑量依(yi)賴性抑(yi)制(zhi)Ca2+內流,抑(yi)制(zhi)NMDA誘導的興(xing)奮性中(zhong)毒效應(ying)。研究表明,在小鼠皮層神經元,Conantokin-G阻(zu)滯NMDA引發的電流信號(hao)的IC50值為480 nM。

 

7. 作用于酸敏感離子通道(ASIC channel, Acid-Sensing Ion Channel)的毒素

Toxin name

Catalog #

Target

APETx2

07APE002

Selective blocker of ASIC3

Psalmotoxin1/PcTx1

13PCT001

Selective blocker of ASIC1a

Ugr9-1

13UGR001

Blocker of ASIC3

 

8. 作用于瞬時受體電位(TRP channel, transient receptor potential)的毒素

Toxin name

Catalog #

Target

GsMTx4

08GSM001

TRPC, TRPA

Vanillotoxin3

10VAN003

Activator of TRPV1

ProTx-I

12PTX001

Antagonist of TRPA1

 

9. 作用于嘌呤能通道(Purinergic channel)的毒素

Purotoxin-1

選擇性(xing)抑制(zhi)P2X3受體(ti)。100 nM Purotoxin-1 (PT-1)選擇性(xing)抑制(zhi)P2X3受體(ti)通(tong)道,在大鼠DRG神經元上(shang),使用膜片鉗實驗(yan)表(biao)明:PT-1對(dui)電(dian)壓(ya)門控通(tong)道和(he)TRPV1均(jun)無抑制(zhi)效應。10 µM ATP和(he)100 µM α,β Methylene-ATP濃(nong)度下(xia)Purotoxin-1對(dui)P2X3受體(ti)有選擇性(xing)作用,在該ATP濃(nong)度下(xia)Purotoxin-1對(dui)P2X2和(he)雜化二聚體(ti)P2X2/3并無激動作用。Purotoxin-1對(dui)疼痛的潛在治療作用。

 

10. 作用于其它膜受體通道(Others)的毒素

Smartox Biotechnology還(huan)提供其他類型(xing)的(de)膜受體抑(yi)制劑(ji):

Toxin name

Catalog #

Target

Morphiceptin

011CAS001

Agonist of µ-opoid receptors

Lys-conopressin G

11CON14

Vasopressin-like peptide

GsMTx4

08GSM001

Mechano sensitive ion channels

Obtustatin

10OBT001

Blocks the binding ;of α1β1  integrin to collagen IV

Rho-Conotoxin TIA

CON022

Blocks α1-adrenergic receptor

 

 

公司簡介

Smartox Biotechnology是*一家(jia)專門(men)生(sheng)(sheng)產動物毒(du)液多(duo)肽毒(du)素(su),用于(yu)細(xi)胞離子通道功能(neng)研究(jiu)的生(sheng)(sheng)物醫(yi)藥公司(si)。多(duo)肽毒(du)素(su)在生(sheng)(sheng)物制(zhi)藥領域(yu)具有重要(yao)的使用價值。

Smartox Biotechnology于2009年(nian)由來自(zi)Grenoble神經(jing)科(ke)學研(yan)(yan)究(jiu)所(Grenoble Institute of Neuroscience)的Michel De Waard博(bo)士創立。Smartox Biotechnology專門研(yan)(yan)究(jiu)動物毒(du)液,制(zhi)作合成多種(zhong)毒(du)液中的多肽成分(常稱為(wei)毒(du)素(su))。De Waard博(bo)士研(yan)(yan)究(jiu)離子通道與毒(du)素(su)多肽的關系(xi),尤(you)其(qi)是鑒定(ding)、開發(fa)毒(du)素(su)多肽作為(wei)治(zhi)療性分子或(huo)細胞穿透肽(cell penetrating peptides, CPP)。其(qi)研(yan)(yan)究(jiu)團(tuan)隊在毒(du)液分離,藥理(li)性活性肽鑒定(ding)、富(fu)半胱(guang)氨(an)酸(suan)肽定(ding)性、制(zhi)作和優(you)化(hua)等方面具有*、豐富(fu)的經(jing)驗。2010年(nian),Smartox Biotechnolgy被法(fa)國研(yan)(yan)究(jiu)部(Ministry of Research)授予“新興企業OSEO獎(OSEO prize for emerging businesses)”。

總(zong)之,Smartox Biotechnolgy提供一系列高質量、具(ju)(ju)開創價值的多肽(tai)毒(du)素(su)(su)。這些化合物在(zai)離子(zi)通(tong)道 研究中(zhong)具(ju)(ju)有高的親和(he)性(xing)和(he)選擇性(xing),是相應領域(yu)科學(xue)研究理想的生物毒(du)素(su)(su)提供商(shang)和(he)貼心(xin)的合作伙伴(ban)。

留言框

  • 產品:

  • 您的單位:

  • 您的姓名:

  • 聯系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算(suan)結果(填寫阿拉伯(bo)數字),如(ru):三加四=7
在線咨(zi)詢
電(dian)話咨詢
13581534696
關注(zhu)微(wei)信